Rochester International Airport (RST) is the closest airport to Mayo Clinic. It is conveniently located just miles south of downtown Rochester, Minnesota and Mayo Clinic.
See how RST makes navigating the airport and city easy for those coming here on business travel!
Photo credit: Paul Flessland
When you fly into Rochester International Airport (RST), it’s easy to get down to business. In fact, you’re just 15 minutes from your next meeting or conference.
With flights into RST from hundreds of cities worldwide on American Airlines and Delta Air Lines, you’ll land just minutes away from downtown Rochester, Minnesota, home of the world-famous Mayo Clinic, without the disruption of navigating from a distant airport.
Choose RST to skip unnecessary drives and dive straight into work upon arrival, saving you (at least) an hour of travel time.
We’re conveniently located less than 20 minutes from downtown Rochester and the world-famous Mayo Clinic so you can get to work – and your next meeting – that much faster.
Effortlessly hop from landing to ride with instant access to convenient taxi or rideshare services directly from the airport gates.
There are several ground transportation operators serving RST. Visit the ground transportation desks upon arrival for taxi, shuttle, and private sedan services. Rideshare service providers such as Lyft and Uber also operate at RST. Signage in the Main Terminal indicates the designated pick-up area.
There are several ground transportation operators serving RST that can provide service from the airport to Mayo Clinic, hotels, or wherever else you need to go.
Visit the ground transportation desks upon arrival for taxi, shuttle, and private sedan services. Rideshare service providers such as Lyft and Uber also operate at RST. Signage in the Main Terminal indicates the designated pick-up area.
Streamlined security checks and check-ins at RST make life easier for busy travelers, giving you more time to catch up on work before your flight.
Call 855.787.2227 in advance of travel with questions about screening policies, procedures, and what to expect at the security checkpoint.
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Updated: January 2026.
Rochester International Airport (RST) strives to ensure that its services are accessible to people with disabilities. Rochester International Airport (RST) has invested a significant amount of resources to help ensure that its website is made easier to use and more accessible for people with disabilities, with the strong belief that every person has the right to live with dignity, equality, comfort, and independence.
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Email: rst@flyrst.com
Phone: 507.282.2328
